Can You Use Hyaluronic Acid With Niacinamide?

Hyaluronic acid and niacinamide are two of the most popular and well-tolerated ingredients in modern skincare. This combination is not only safe but is highly recommended by dermatologists and cosmetic chemists for its complementary effects. Both ingredients are water-soluble and integrate seamlessly into a daily routine, making them an excellent pairing for nearly all skin types.

The Perfect Pairing: Why They Work Together

The compatibility of hyaluronic acid and niacinamide stems from their chemical stability and differing mechanisms of action. Niacinamide, a form of Vitamin B3, is stable and effective across a broad pH range, which aligns closely with the skin’s natural slightly acidic pH. Hyaluronic acid is also typically formulated within this range, meaning neither ingredient destabilizes the other when applied sequentially or combined in a single product.

These two ingredients do not compete for absorption pathways or neutralize each other’s effects because they perform entirely different functions. Hyaluronic acid acts as a humectant, drawing moisture from the environment into the skin’s surface layers. Niacinamide, conversely, functions as a cell-communicating ingredient that supports the skin’s internal structure. Both are generally non-irritating, which makes them suitable for simultaneous use, even for individuals with sensitive skin.

Synergistic Skin Benefits

The combination addresses both hydration and barrier function simultaneously. Hyaluronic acid is renowned for its ability to bind and retain large amounts of water. This intense hydration immediately plumps the skin, which helps to reduce the appearance of fine lines and surface texture.

Niacinamide complements this hydration by strengthening the skin’s natural defenses. It supports the production of ceramides, which are lipids that form the skin barrier, thereby reducing transepidermal water loss (TEWL). By improving the barrier, niacinamide effectively locks in the moisture that hyaluronic acid has drawn into the skin. Furthermore, niacinamide helps to regulate sebum production and minimize the appearance of pores, while its anti-inflammatory properties can reduce redness and blotchiness.

How to Layer for Maximum Effectiveness

Incorporating this duo into a routine is straightforward, following the general rule of applying products from the thinnest consistency to the thickest. A common and effective method is to apply the thinner product first, which is often the hyaluronic acid serum, immediately after cleansing.

A practical tip for maximizing the humectant properties of hyaluronic acid is to apply it to slightly damp skin. The presence of water on the skin’s surface gives the hyaluronic acid a source of moisture to draw from, enhancing its plumping effect. Once the hyaluronic acid has absorbed, the niacinamide serum can be applied next to deliver its barrier-strengthening and oil-regulating benefits. Both ingredients are suitable for use in both morning and evening routines.